"He's still in protocols and he needs ramp up, so we won't see Kyrie on this trip," Nash said. "I honestly don't know what the rule change will be our how it'll affect us, but I guess anything's possible and we'll see when the time comes. But right now, I couldn't answer that."
Nash added that Blake Griffin's knee is fine after a bout of tightness stemming from last Saturday's 100-93 loss to the Orlando Magic.
However, seven Brooklyn players remain quarantined -- the team announced later Friday that Bruce Brown and James Johnson cleared protocols and are available -- entering a prime-time matchup between the Eastern Conference-leading Nets (21-9) and sub-.500 Lakers (16-17).
"I mean, we've only been allowed to do some ... work for a couple days now," Nash said. "Most of the guys have had just basically little workouts, just with the coach and themselves. (Friday) we were able to have a little bit of a practice, where we did some technical things and actually got up and down (the court) a little bit.
"These guys haven't been able to get up and down, so it's important -- I think -- that they got a little bit in their legs today before playing an NBA game (Saturday). But you can't, obviously, overdo it as well because they have to try to play (Saturday). So we tried to walk that line the best we could and we'll see what we have in the tank (Saturday)."